Do NOT drink alcohol or usage abuse illicit drugs, street medicines or various other opioids while taking tramadol. Nonetheless, serotonin syndrome as well as raised seizure risk can occur with lots of various other medicines, too. Individuals getting serotonergic medications (for example, the migraine headache class called "triptans") may additionally go to a greater threat for serotonin disorder. Your physician might require to readjust your tramadol dose or cease therapy based upon exactly how it influences your breathing. Tramadol has a long checklist of major and potentially fatal reactions.