Conditions of destitution are illness that are connected with destitution as well as reduced social status; diseases of affluence are illness that are associated with high social and economic status. Which diseases are associated with which states vary according to location, time, as well as innovation? Some diseases, such as diabetes mellitus, may be connected with both hardship (poor food selections) as well as affluence (less active lifestyles as well as long life-spans), with different systems.